Showing posts with label vectors. Show all posts
Showing posts with label vectors. Show all posts

Thursday, 31 December 2015

How the murderer achieves to penetrate a really complex security system?

I am gonna explain the mechanism of commiting murder used by this relentless virus. 


Image 4.1. Insects being 
vectors of the virus

First of all, this murderer has to be transmitted from somewhere, and this Bromoviridae family virus, arrives to the host in two possible ways. The first, by a mechanical inoculation in plant by an insect, and the second is even simple, staying in contact one plant with another


Image 4.2. Vegetable cells that
shows easily the tonoplast


After have penetrated on it, Cucumovirus has succeed one of his objectives necessaries to commit the crime: entering to a vegetable cell. When staying inside it starts to uncoat, what implicates to release the viral nucleic acids from the capsid, liberating the viral genomic RNA into the cytoplasm, contained inside the virus cell sorrounded by the capsid; causing the expression of the first and second protein, what produces the recplication proteins, responsible for synthetising the RNA strands, in a viral factory, that can be different types of organelles, in concrete, the accomplice of giving home to this criminal is the vacuoles membrane or also called tonolpast. 

Image 4.3. Electronic micrscope
photo of a bascular bundle cells
And the crime starts! 
It produces a transcribement of the complete RNA genome, providing new viral RNA genomes in order to multiply the CMV to the whole plant, but it can really go somewhere alone? No, there must be something controlling it and this is not other than the capsid, a organelle that mantains everything to it position, so can, now, moves. Finally the viral movement protein triggers the formation of tubular structures called plasmodesmatas what allows the murderer to move from one host to the other next to it.


Image 4.4. Picture displaying the transport plasmodesmata system

But "when more you have, more you want", hence the Cucumovirus not happy by infecting mature cells, it transports cell-to-cell, traspassing different cells as Sclerenchyma, Collechyma, Parenchyma and Xyle, aiming to arrive to the phloem so can be transported easily to the green shots, his ambitious objective.

Image 4.5. Explicative picture of bascular bundle cells